Primary CNS Lymphoma is a disease in which malignant (cancer) cells form in the lymph tissue of the brain and/or spinal cord. It often occurs in immunosuppressed patients and in association with the Epstein-Barr virus. In non-immunosuppressed patients, it is not associated with the Epstein-Barr virus. This condition may mimic non-neoplastic disorders such as sarcoidosis, multiple sclerosis or other demyelinating process.In non-immunosuppressed patients, it is not associated with the Epstein-Barr virus. This condition may mimic non-neoplastic disorders such as sarcoidosis, multiple sclerosis or other demyelinating process.
Signs and symptoms
- Visual Deficits
- Personality/Behavioral Changes
Note: these are just a few signs and symptoms provided for informational purposes. Do not attempt self-diagnosis based on this list.
Although the initial diagnosis may be suggested by neuroimaging, a more definitive diagnosis is made by brain biopsy, CSF analysis, or vitreal biopsy if there is ocular involvement. Studies show that less than 5% of cases are associated with systemic lymphoma. Primary CNS lymphoma is treated with both radiation and chemotherapy and in some cases monoclonal antibodies have been added to the treatment regimen. Whole-brain radiation with or without methotrexate or other chemotherapy can result in delayed neurotoxicity which can result in decline in cognitive functions, urinary incontinence and ataxia.
Northern Neurology Specialties, Dr. Jill Bressler – CNS Lymphoma Treatment
Although rare, these esoteric conditions are eventually looked at in a potential diagnosis where we have ruled out many other conditions. Our first plan of action is a confirmed diagnosis. Once we confirm a diagnosis, Northern Neurology Specialties and Dr. Jill Bressler will refer you to a neuro-oncologist and others within the medical field and all will collaborate and effectively come up with a treatment plan with the patient and family. Call us today if you are experiencing any of these symptoms.